Description

1-(5-Bromo-1H-Indol-3-Yl)-2,2,2-Trichloroethanone is a specialized halogenated indole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both bromo-indole and trichloroacetyl moieties, makes it a versatile building block for constructing complex heterocyclic frameworks. This high-purity compound is primarily utilized by research institutions and pharmaceutical development teams engaged in medicinal chemistry and agrochemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its halogenated structure.
• Material Science: Serves as a monomer or cross-linking agent in the research of advanced polymers and functional materials.
• Organic Synthesis: A valuable reagent for constructing complex indole-based alkaloids and other natural product analogs in academic and industrial R&D.
• Bioconjugation Chemistry: Potential use in creating labeled probes or affinity ligands due to its reactive ketone group.

Basic Information

Product Name	1-(5-Bromo-1H-Indol-3-Yl)-2,2,2-Trichloroethanone
CAS No.	1336879-56-1
Molecular Formula	C10H5BrCl3NO
Molecular Weight	341.41 g/mol
Synonyms	5-Bromo-1H-indole-3-carboxylic acid trichloromethyl ketone; 5-Bromo-3-(trichloroacetyl)indole; 2,2,2-Trichloro-1-(5-bromo-1H-indol-3-yl)ethanone; 1-(5-Bromo-1H-indol-3-yl)-2,2,2-trichloroethan-1-one; 5-Bromo-α,α,α-trichloro-1H-indole-3-acetophenone; 3-(Trichloroacetyl)-5-bromoindole
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-1H-Indol-3-Yl)-2,2,2-Trichloroethanone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.