Description

4-((3R)-3-Piperidyl)Benzoic Acid CAS NO 1336552-91-0 is a high-purity chiral building block featuring a benzoic acid moiety linked to a stereodefined piperidine ring. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutic areas.
• Ligand and Catalyst Precursor: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Serves as a building block for developing advanced, stereoselective pesticides and herbicides.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions.
• Peptidomimetic Research: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4-((3R)-3-Piperidyl)Benzoic Acid
CAS No.	1336552-91-0
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	4-[(3R)-3-Piperidinyl]benzoic acid; (R)-4-(3-Piperidyl)benzoic Acid; Benzoic acid, 4-[(3R)-3-piperidinyl]-; 4-((R)-Piperidin-3-yl)benzoic acid; (R)-3-(4-Carboxyphenyl)piperidine; 1336552-91-0; 4-(3R-Piperidin-3-yl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-((3R)-3-Piperidyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.