Description

5-(4-Chloroquinazolin-6-Yl)Furan-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazoline-furan hybrid structure. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on oncology, kinase inhibitors, and other targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Employed in the development of chemical probes to study enzyme function and biological pathways.
• Organic Synthesis: Serves as a versatile electrophile for condensation and cyclization reactions to create complex heterocyclic libraries.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	5-(4-Chloroquinazolin-6-Yl)Furan-2-Carbaldehyde
CAS No.	1334953-76-2
Molecular Formula	C₁₃H₇ClN₂O₂
Molecular Weight	258.66 g/mol
Synonyms	5-(4-Chloro-6-quinazolinyl)-2-furancarboxaldehyde; 2-Furaldehyde, 5-(4-chloro-6-quinazolinyl)-; 5-(4-Chloroquinazolin-6-yl)furan-2-carboxaldehyde; 5-(4-Chloro-6-quinazolyl)furfural; 4-Chloro-6-(5-formylfuran-2-yl)quinazoline; 6-(5-Formylfuran-2-yl)-4-chloroquinazoline
EINECS	Contact for details

Quality Control

Our 5-(4-Chloroquinazolin-6-Yl)Furan-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.