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2-Amino-6-Chloro-1,2,3,4-Tetrahydronaphthalene Hcl CAS NO 1334509-90-8


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CAS No.:1334509-90-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-6-Chloro-1,2,3,4-Tetrahydronaphthalene Hcl is a high-purity, pharmaceutically relevant organic intermediate in the form of a hydrochloride salt. This compound matters as a critical building block for the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of novel therapeutic agents, where its defined structure and purity are essential for successful outcomes.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly for central nervous system (CNS) targets.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic compounds.
  • Chemical Synthesis Building Block: Employed in multi-step organic synthesis to construct complex polycyclic or fused-ring molecular architectures.
  • Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
  • Academic & Institutional Research: Applied in university and institutional labs for fundamental research in organic synthesis and pharmacology.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name 2-Amino-6-Chloro-1,2,3,4-Tetrahydronaphthalene Hydrochloride
CAS No. 1334509-90-8
Molecular Formula C10H13ClN • HCl
Molecular Weight 218.13 g/mol (Free base: 181.67 g/mol)
Synonyms 6-Chloro-1,2,3,4-tetrahydro-2-naphthylamine hydrochloride; 2-Amino-6-chloro-1,2,3,4-tetrahydronaphthalene hydrochloride; 6-Chloro-2-tetralinamine hydrochloride; 2-Naphthalenamine, 6-chloro-1,2,3,4-tetrahydro-, hydrochloride (1:1); 6-Chloro-1,2,3,4-tetrahydro-naphthalen-2-ylamine hydrochloride
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Quality Control

Our 2-Amino-6-Chloro-1,2,3,4-Tetrahydronaphthalene Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP standards for pharmaceutical intermediates, and our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Single Unknown Impurity (HPLC) ≤0.5%
Total Impurities (HPLC) ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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