Description

4-(3-Chloro-5-Fluorophenyl)Phenylacetic Acid is a high-purity, halogenated phenylacetic acid derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both chloro and fluoro substituents onto a biphenylacetic acid core, facilitating the development of novel compounds with tailored properties. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Research: Used in the synthesis of specialized organic molecules for electronic displays and optoelectronic devices due to its rigid, substituted biphenyl core.
• Fine Chemical Production: Employed as a versatile building block for creating complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: An essential reagent for methodological studies in organic chemistry, including cross-coupling reactions and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	4-(3-Chloro-5-Fluorophenyl)Phenylacetic Acid
CAS No.	1334499-97-6
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	[4-(3-Chloro-5-fluorophenyl)phenyl]acetic acid; 2-[4-(3-Chloro-5-fluorophenyl)phenyl]acetic acid; 4-(3-Chloro-5-fluorophenyl)benzeneacetic acid; 3-Chloro-5-fluoro-4'-carboxymethylbiphenyl; (4'-3-Chloro-5-fluorobiphenyl-4-yl)acetic acid; 4-(3-Chloro-5-fluorophenyl)benzenacetic acid; Biphenyl-4-acetic acid, 3'-chloro-5'-fluoro- derivative
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-5-Fluorophenyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.