Description

6-Bromo-2,4-Dihydrospiro[1,5-Benzodioxepine-3,1'-Cyclopropane] is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and heterocyclic fused-ring structure. This compound is of significant value in medicinal chemistry for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its spirocyclic scaffold.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the synthesis of more complex heterocyclic compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	6-Bromo-2,4-Dihydrospiro[1,5-Benzodioxepine-3,1'-Cyclopropane]
CAS No.	1334499-94-3
Molecular Formula	C12H11BrO2
Molecular Weight	267.12 g/mol
Synonyms	6-Bromo-2,4-dihydrospiro[1,5-benzodioxepine-3,1'-cyclopropane]; 6-Bromospiro[1,5-benzodioxepine-3,1'-cyclopropane]-2,4-dihydro; Spiro[cyclopropane-1,3'-[1,5]benzodioxepin]-6'-bromo-2',4'-dihydro; 6-Bromo-2,4-dihydrospiro[1,5]benzodioxepine-3,1'-cyclopropane; 1334499-94-3
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2,4-Dihydrospiro[1,5-Benzodioxepine-3,1'-Cyclopropane] is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.