Description

4-Chloro-3-Ethylquinoline-8-Carbonitrile is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Organic Synthesis Building Block: The chloro, ethyl, and nitrile functional groups offer multiple sites for further chemical modification (e.g., cross-coupling, nucleophilic substitution, reduction).
• Material Science: Investigated as a precursor for the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty dyes.
• Chemical Research & Development: Employed in academic and industrial R&D for method development and exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-3-Ethylquinoline-8-Carbonitrile
CAS No.	1334499-57-8
Molecular Formula	C₁₂H₉ClN₂
Molecular Weight	216.67 g/mol
Synonyms	8-Cyano-4-chloro-3-ethylquinoline; 3-Ethyl-4-chloroquinoline-8-carbonitrile; 4-Chloro-3-ethyl-8-quinolinecarbonitrile; Quinoline-8-carbonitrile, 4-chloro-3-ethyl-; 1334499-57-8
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Ethylquinoline-8-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.