Description

Chloro(Crotyl)[Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine]Palladium(II) is a highly specialized, air-stable palladium catalyst featuring a bulky, electron-rich phosphine ligand. This compound is engineered to provide superior catalytic activity and selectivity in challenging cross-coupling reactions, offering researchers and process chemists a reliable tool for constructing complex molecular architectures. It is primarily utilized in advanced pharmaceutical research, agrochemical development, and materials science for the synthesis of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi cross-coupling reactions in API development.
• Agrochemical Research: Enables the efficient construction of complex heterocyclic compounds used in novel crop protection agents.
• Materials Science: Facilitates C-C and C-N bond formation in the synthesis of organic semiconductors and advanced polymeric materials.
• Process Chemistry Optimization: Valued for its stability and reactivity in scaling up coupling reactions from lab to pilot plant scale.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring precise, selective bond formation.

Basic Information

Product Name	Chloro(Crotyl)[Di-tert-Butyl(4-Dimethylaminophenyl)Phosphine]Palladium(II)
CAS No.	1334497-06-1
Molecular Formula	C19H31ClNPPd
Molecular Weight	458.27 g/mol
Synonyms	Chloro(crotyl)(di-tert-butyl(4-dimethylaminophenyl)phosphine)palladium; Pd(dtbpf)Cl(crotyl); Di-tert-butyl(4-dimethylaminophenyl)phosphine-crotylpalladium(II) chloride; Crotylpalladium(II) chloride dtbpf complex; (2-Butenyl)palladium chloride complex with Di-tert-butyl(4-dimethylaminophenyl)phosphine; Palladium, chloro(2-butenyl)[[4-(dimethylamino)phenyl]di-tert-butylphosphine]-; DTBPF-Pd(crotyl)Cl; CAS 1334497-06-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Each batch is characterized by NMR (1H, 31P) and elemental analysis to confirm identity and purity. Certificates of Analysis (COA) detailing assay, impurity profiles, and physical properties are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container under an inert atmosphere (argon or nitrogen), protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; handle and store under inert conditions to maintain stability and catalytic performance. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Orange to brown crystalline solid or powder
Identification (NMR)	Conforms to structure
Assay (Pd content)	≥ 95.0% (by elemental analysis)
Purity (NMR)	≥ 97.0%
Solubility	Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.