Description

(3-Fluorocyclobutyl)Methamine Hydrochloride is a high-purity fluorinated building block and amine hydrochloride salt of significant interest in advanced organic synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the fluorinated cyclobutyl scaffold, which is crucial for modulating the biological activity and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry Building Block: Used to introduce the fluorinated cyclobutylamine moiety into lead compounds to optimize potency, selectivity, and pharmacokinetic properties.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides where the fluorine atom enhances bioactivity and environmental stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Acts as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Peptidomimetics: Incorporated into peptide analogs to create more stable and bioavailable therapeutic candidates.

Basic Information

Product Name	(3-Fluorocyclobutyl)Methamine Hydrochloride
CAS No.	1334493-19-4
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol
Synonyms	1-(3-Fluorocyclobutyl)methanamine hydrochloride; (3-Fluorocyclobutyl)methylamine hydrochloride; 3-Fluorocyclobutanemethanamine hydrochloride; 1-(3-Fluorocyclobutyl)methanamine HCl; 3-Fluorocyclobutylmethylamine HCl; (3-Fluorocyclobutyl)methanamine hydrochloride; 3-Fluorocyclobutanemethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Fluorocyclobutyl)Methamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.