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(2R,4S)-3-[(R)-(I-Propyl)(1-Methyl-1H-Imidazol-2-Yl)Methyl]-4-(I-Propyl)-2-Methoxyoxazolidine, 99% CAS NO 1334170-82-9


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CAS No.:1334170-82-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R,4S)-3-[(R)-(I-Propyl)(1-Methyl-1H-Imidazol-2-Yl)Methyl]-4-(I-Propyl)-2-Methoxyoxazolidine, 99% is a high-purity, chiral oxazolidine derivative featuring a unique imidazole substituent. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile organocatalyst or ligand in asymmetric synthesis. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require precise stereochemical control for developing novel active ingredients and specialty molecules.

Application

  • Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
  • Asymmetric Organocatalysis: Serves as a catalyst or catalyst precursor for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
  • Ligand in Metal-Catalyzed Reactions: Used as a chiral ligand for transition metals to facilitate asymmetric hydrogenation, cross-coupling, and other catalytic transformations.
  • Agrochemical Research: Employed in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
  • Academic & Process R&D: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial research laboratories.
  • Material Science: Potential precursor for chiral polymers or functional materials with specific optical properties.

Basic Information

Product Name (2R,4S)-3-[(R)-(I-Propyl)(1-Methyl-1H-Imidazol-2-Yl)Methyl]-4-(I-Propyl)-2-Methoxyoxazolidine, 99%
CAS No. 1334170-82-9
Molecular Formula C15H27N3O2
Molecular Weight 281.40 g/mol
Synonyms (2R,4S)-3-[(R)-(Isopropyl)(1-Methyl-1H-Imidazol-2-yl)Methyl]-4-(Isopropyl)-2-Methoxyoxazolidine; (2R,4S)-3-[(R)-(1-Methyl-1H-imidazol-2-yl)(propan-2-yl)methyl]-4-(propan-2-yl)-2-methoxy-1,3-oxazolidine; Chiral Imidazole-Oxazolidine Catalyst; 2-Methoxyoxazolidine Derivative; Asymmetric Synthesis Intermediate; Organocatalyst Ligand; Contact for additional synonyms.
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Quality Control

Our 99% pure grade of this chiral intermediate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 99.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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