Description

(2-Aminoethyl)(2,2,2-Trifluoroethyl)Amine Dihydrochloride is a high-purity, specialty organic salt featuring both amino and trifluoroethyl functional groups. This compound is valued for its role as a versatile building block in advanced pharmaceutical and agrochemical synthesis, where its unique fluorine-containing structure can impart desirable metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science research sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Chelator Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal ion complexation.
• Bioconjugation and Linker Chemistry: The primary amine group enables its use in constructing cleavable linkers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science Research: Employed in the development of fluorinated polymers and specialty coatings with unique surface properties.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent or affinity probes to study biological processes.

Basic Information

Product Name	(2-Aminoethyl)(2,2,2-Trifluoroethyl)Amine Dihydrochloride
CAS No.	1334147-63-5
Molecular Formula	C4H10F3N2 • 2HCl
Molecular Weight	231.06 g/mol
Synonyms	N-(2-Aminoethyl)-2,2,2-trifluoroethanamine dihydrochloride; 2,2,2-Trifluoro-N-(2-aminoethyl)ethanamine dihydrochloride; 1,1,1-Trifluoro-2-[(2-aminoethyl)amino]ethane dihydrochloride; N1-(2,2,2-Trifluoroethyl)ethylenediamine dihydrochloride; TFEA Dihydrochloride; 2-[(2,2,2-Trifluoroethyl)amino]ethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (2-Aminoethyl)(2,2,2-Trifluoroethyl)Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.