Description

3-Bromo-5,6-Dimethoxypicolinonitrile is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromo and nitrile functionalities into pyridine-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other small molecule drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or components for OLEDs.
• Chemical Biology Probes: Acts as a starting point for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific custom synthesis projects requiring this specific bromo-nitrile picolinate derivative.

Basic Information

Product Name	3-Bromo-5,6-Dimethoxypicolinonitrile
CAS No.	1333147-36-6
Molecular Formula	C8H7BrN2O2
Molecular Weight	243.06 g/mol
Synonyms	3-Bromo-5,6-dimethoxypicolinonitrile; 5,6-Dimethoxy-3-bromopicolinonitrile; 3-Bromo-5,6-dimethoxy-2-cyanopyridine; 2-Pyridinecarbonitrile, 3-bromo-5,6-dimethoxy-; 3-Bromo-5,6-dimethoxypyridine-2-carbonitrile; 3-Bromo-5,6-dimethoxy-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5,6-Dimethoxypicolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.