Description

3-(2-Methoxyphenyl)Oxetan-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1332765-89-5. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and manufacturing who require reliable, high-quality intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a key starting material for the development and scale-up of synthetic routes to target APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for studying oxetane chemistry and developing new synthetic methodologies.

Basic Information

Product Name	3-(2-Methoxyphenyl)Oxetan-3-Amine Hydrochloride
CAS No.	1332765-89-5
Molecular Formula	C10H14ClNO2
Molecular Weight	215.68 g/mol
Synonyms	3-Amino-3-(2-methoxyphenyl)oxetane hydrochloride; 3-(2-Methoxyphenyl)-3-oxetanamine hydrochloride; 2-Methoxy-α-(oxetan-3-yl)benzenemethanamine hydrochloride; Oxetan-3-amine, 3-(2-methoxyphenyl)-, hydrochloride; 1332765-89-5
EINECS	Contact for details

Quality Control

Our 3-(2-Methoxyphenyl)Oxetan-3-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical development, and custom purity grades or analytical packages can be discussed to support specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.