Description

4-Methyl-1,2,3,4-Tetrahydroquinoline-6-Carboxylic Acid is a high-value, functionalized tetrahydroquinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure with both carboxylic acid and saturated nitrogen heterocycle functionalities makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its electron-donating and complexing properties.
• Dye and Pigment Intermediate: Functions as a building block for synthesizing specialized quinoline-based dyes and colorants.

Basic Information

Product Name	4-Methyl-1,2,3,4-Tetrahydroquinoline-6-Carboxylic Acid
CAS No.	1332627-30-1
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	6-Carboxy-4-methyl-1,2,3,4-tetrahydroquinoline; 4-Methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid; 1,2,3,4-Tetrahydro-4-methyl-6-quinolinecarboxylic acid; 4-Methyl-5,6,7,8-tetrahydroquinoline-2-carboxylic acid (tautomeric form); MTQCA; 4-Me-THQ-6-COOH
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-1,2,3,4-Tetrahydroquinoline-6-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.