Description

2-Methyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid is a high-purity, functionalized tetrahydroquinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, multifunctional scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the quinoline core for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: The carboxylic acid and nitrogen-containing heterocycle make it a valuable precursor for designing novel chiral ligands and metal-organic catalysts.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinoline-based dyes and colorants for high-performance applications.
• Academic and Contract Research: A valuable reagent for methodological studies and the construction of complex natural product analogs in university and CRO laboratories.

Basic Information

Product Name	2-Methyl-1,2,3,4-tetrahydroquinoline-8-carboxylic Acid
CAS No.	1332627-29-8
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	8-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-methyl-; 2-Methyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid; 2-Methyl-5,6,7,8-tetrahydroquinoline-8-carboxylic acid; 2-Methyl-5,6,7,8-tetrahydro-8-quinolinecarboxylic acid; 8-Carboxy-2-methyl-1,2,3,4-tetrahydroquinoline; MTQCA; 1332627-29-8
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.