Description

1-(1-Adamantyl)-3,5-Dimethyl-1,2,3,6-Tetrahydropyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique adamantane-modified tetrahydropyridine structure. This compound is valued for its role as a critical building block in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and antiviral research. It is essential for medicinal chemistry R&D and process development teams in the pharmaceutical and biotechnology industries seeking to develop next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), especially for neurological and antiviral targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its adamantyl group, which can enhance lipophilicity and receptor binding.
• Process Chemistry & Scale-Up: Serves as a standardized building block for process development and the manufacture of clinical trial materials.
• Biochemical Tool Compound: Employed in pharmacological assays and as a reference standard for analytical method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for cutting-edge organic synthesis and drug discovery projects.
• Custom Synthesis Starting Material: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs to create bespoke molecular libraries.

Basic Information

Product Name	1-(1-Adamantyl)-3,5-Dimethyl-1,2,3,6-Tetrahydropyridine Hydrochloride
CAS No.	1332529-59-5
Molecular Formula	C17H28ClN
Molecular Weight	281.86 g/mol
Synonyms	1-(1-Adamantyl)-3,5-dimethyl-1,2,3,6-tetrahydropyridine HCl; 1-Adamantyl-3,5-dimethyl-1,2,3,6-tetrahydropyridine hydrochloride; 3,5-Dimethyl-1-(tricyclo[3.3.1.1³,⁷]dec-1-yl)-1,2,3,6-tetrahydropyridine hydrochloride; Adamantyl-dimethyl-tetrahydropyridine HCl; ADTP-HCl
EINECS	Contact for details

Quality Control

Our 1-(1-Adamantyl)-3,5-Dimethyl-1,2,3,6-Tetrahydropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.