Description

2-(1-Adamantyl)-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique adamantane-tetrahydroisoquinoline hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly for its potential role in modulating central nervous system (CNS) targets. It is primarily sought by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in the synthesis of novel therapeutic agents for neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the pharmacological profile of adamantane-containing compounds.
• CNS Drug Development: Investigated for potential applications in developing treatments for conditions such as Parkinson's disease, depression, and cognitive disorders.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions within biological systems.
• Process Chemistry & Scale-up: Supplied for route scouting and optimization during the transition from laboratory-scale to pilot-plant synthesis.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-(1-Adamantyl)-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1332529-46-0
Molecular Formula	C19H26ClN
Molecular Weight	303.87 g/mol
Synonyms	2-(1-Adamantyl)-1,2,3,4-tetrahydroisoquinoline HCl; 2-Adamantan-1-yl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-2-(1-adamantyl)isoquinoline hydrochloride; 2-(Tricyclo[3.3.1.1³,⁷]dec-1-yl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; Adamantyltetrahydroisoquinoline HCl; ATIQ HCl
EINECS	Contact for details

Quality Control

Every batch of 2-(1-Adamantyl)-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.