Description

1-Boc-1,6-Diazaspiro[3.3]Heptane Oxalate is a high-purity, protected diazaspiro compound used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this high-quality intermediate to construct complex molecular architectures with precision and reliability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs), especially for CNS-targeted drugs.
• Medicinal Chemistry: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its spirocyclic and protected amine functionalities.
• Chemical Biology: Serves as a scaffold or linker in the development of chemical probes and PROTACs (Proteolysis Targeting Chimeras).
• Agrochemical Research: Employed as a building block in the discovery and synthesis of novel crop protection agents.
• Academic Research: Utilized in universities and research institutes for methodological development and the study of spirocyclic compound properties.
• Peptidomimetics: Acts as a constrained, rigid analog in the design of peptide mimics to enhance metabolic stability and bioavailability.

Basic Information

Product Name	1-Boc-1,6-Diazaspiro[3.3]Heptane Oxalate
CAS No.	1330763-95-5
Molecular Formula	C14H22N2O6
Molecular Weight	314.33 g/mol
Synonyms	1,6-Diazaspiro[3.3]heptane, 1-(1,1-dimethylethyl) 1,6-dicarboxylate, oxalic acid salt; tert-Butyl 1,6-diazaspiro[3.3]heptane-1-carboxylate oxalate; 1-Boc-1,6-diazaspiro[3.3]heptane oxalic acid salt; 1-N-Boc-1,6-diazaspiro[3.3]heptane oxalate; 1-(tert-Butoxycarbonyl)-1,6-diazaspiro[3.3]heptane oxalate; BOC-Diazaspiroheptane Oxalate; 1330763-95-5
EINECS	Contact for details

Quality Control

Our 1-Boc-1,6-Diazaspiro[3.3]Heptane Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.