Description

6-Chloro-3-Iodo-1H-Quinolin-4-One is a halogenated quinolinone derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both chlorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other bioactive heterocyclic compounds.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core.
• Material Science: Acts as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions due to the reactivity of its halogen atoms.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Academic & Institutional Research: A valuable reagent for methodological studies and exploring new synthetic pathways in university and R&D laboratory settings.

Basic Information

Product Name	6-Chloro-3-Iodo-1H-Quinolin-4-One
CAS No.	1330754-24-9
Molecular Formula	C9H5ClINO
Molecular Weight	305.50 g/mol
Synonyms	6-Chloro-3-iodoquinolin-4(1H)-one; 3-Iodo-6-chloro-1H-quinolin-4-one; 4(1H)-Quinolinone, 6-chloro-3-iodo-; 6-Chloro-3-iodo-4-hydroxyquinoline; 6-Chloro-3-iodo-4-quinolone
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Iodo-1H-Quinolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and high performance in your applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.