Description

6-Amino-2,3-Difluorophenol Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its unique difluorophenol core, which is critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of novel polymers and advanced organic materials with specific electronic or optical properties.
• Fluorination Chemistry Studies: Acts as a model compound in academic and industrial research focused on fluorinated aromatic systems.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring a functionalized, fluorinated phenol derivative.

Basic Information

Product Name	6-Amino-2,3-Difluorophenol Hydrochloride
CAS No.	1330750-27-0
Molecular Formula	C6H5ClF2NO
Molecular Weight	189.56 g/mol
Synonyms	2,3-Difluoro-6-aminophenol Hydrochloride; 6-Amino-2,3-difluorophenol HCl; 2-Amino-3,4-difluorophenol Hydrochloride; 3,4-Difluoro-2-aminophenol Hydrochloride; Phenol, 6-amino-2,3-difluoro-, hydrochloride; 1330750-27-0; 6-Amino-2,3-difluorophenol monohydrochloride
EINECS	Contact for details

Quality Control

Our 6-Amino-2,3-Difluorophenol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.