Description

8-(2,3,4-Trifluorophenyl)-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluorophenyl-triazolopyridine scaffold. This compound is of significant commercial value for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers engaged in creating new molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atoms for improved lipophilicity and target binding.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials due to its rigid, conjugated structure.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe or inhibitor to study specific enzymatic pathways and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	8-(2,3,4-Trifluorophenyl)-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine
CAS No.	1329673-31-5
Molecular Formula	C12H7F3N4
Molecular Weight	264.21 g/mol
Synonyms	8-(2,3,4-Trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 8-(2,3,4-Trifluorophenyl)-1,2,4-triazolo[1,5-a]pyridin-2-amine; 1329673-31-5; 8-(2,3,4-Trifluorophenyl)-1,2,4-triazolo[1,5-a]pyridine-2-amine; 2-Amino-8-(2,3,4-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyridine; 8-(2,3,4-Trifluorophenyl)-1,2,4-triazolo[1,5-a]pyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We support development and commercial projects with consistent quality, from milligram to kilogram scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.