Description

4,6-Difluoro-1-Methyl-1H-Indazole-5-Carboxylic Acid is a high-value fluorinated indazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and anti-cancer agent discovery.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and pesticides, where the difluoro substitution pattern can enhance bioavailability and target binding.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	4,6-Difluoro-1-Methyl-1H-Indazole-5-Carboxylic Acid
CAS No.	1329166-90-6
Molecular Formula	C9H6F2N2O2
Molecular Weight	212.16 g/mol
Synonyms	1-Methyl-4,6-difluoro-1H-indazole-5-carboxylic acid; 4,6-Difluoro-1-methyl-1H-indazole-5-carboxylic acid; 5-Carboxy-4,6-difluoro-1-methylindazole; 1329166-90-6; 1H-Indazole-5-carboxylic acid, 4,6-difluoro-1-methyl-
EINECS	Contact for details

Quality Control

Our production of 4,6-Difluoro-1-Methyl-1H-Indazole-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.