Description

n-(3-Bromo-2-Methyl-6-Nitrophenyl)-2,2,2-Trifluoroacetamide is a specialized, high-purity trifluoroacetamide derivative with a bromo-nitrophenyl backbone. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive nitro and halogen substituents.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for introducing the trifluoroacetamide and bromo functional groups.
• Material Science: Potential monomer or additive in the development of specialty polymers and advanced functional materials.
• Chemical Biology & Proteomics: Can be utilized as a reagent or probe in biochemical research and protein studies.
• Dye & Pigment Intermediate: Serves in the synthesis of complex nitro-aromatic based dyes and pigments.

Basic Information

Product Name	n-(3-Bromo-2-Methyl-6-Nitrophenyl)-2,2,2-Trifluoroacetamide
CAS No.	1325729-87-0
Molecular Formula	C10H6BrF3N2O3
Molecular Weight	339.07 g/mol
Synonyms	2,2,2-Trifluoro-N-(3-bromo-2-methyl-6-nitrophenyl)acetamide; 3'-Bromo-2'-methyl-6'-nitro-2,2,2-trifluoroacetamilide; N-(3-Bromo-2-methyl-6-nitrophenyl)trifluoroacetamide; TFA Amide of 3-Bromo-2-methyl-6-nitroaniline; 1325729-87-0; 3-Bromo-2-methyl-6-nitrotrifluoroacetamilide
EINECS	Contact for details

Quality Control

Our production of n-(3-Bromo-2-Methyl-6-Nitrophenyl)-2,2,2-Trifluoroacetamide adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.