Description

5-Quinolinecarboxylic Acid, 7-Fluoro-2-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-3-(1-Methyl-1H-1,2,4-Triazol-5-Yl)-4-Oxo-, Methyl Ester is a sophisticated heterocyclic building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which incorporates multiple pharmacologically relevant motifs, including a quinoline core, fluorinated phenyl groups, and a methylated triazole moiety. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and as a key intermediate in discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fluorinated quinoline-triazole hybrid structure.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific enzyme interactions or biological pathways.
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical suppliers offering bespoke synthesis services for client-specific R&D projects.

Basic Information

Product Name	5-Quinolinecarboxylic Acid, 7-Fluoro-2-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-3-(1-Methyl-1H-1,2,4-Triazol-5-Yl)-4-Oxo-, Methyl Ester
CAS No.	1322616-36-3
Molecular Formula	C21H17F2N5O3
Molecular Weight	425.39 g/mol
Synonyms	7-Fluoro-2-(4-fluorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-1,2,4-triazol-5-yl)-4-oxo-5-quinolinecarboxylic acid methyl ester; Methyl 7-fluoro-2-(4-fluorophenyl)-3-(1-methyl-1H-1,2,4-triazol-5-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate; 1322616-36-3; UNII-9G6Q4K8V3I; 9G6Q4K8V3I; BDBM50190073; AKOS025310923; A1-03449
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical characterization, including HPLC for purity assessment, NMR and MS for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring full traceability and compliance with client specifications. Quality systems are designed to support development from research to GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.