Description

(6-Fluoro-2-Methyl-4-Oxo-4H-Quinazolin-3-Yl)-Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct quinazolinone-acetic acid structure. This compound matters as a critical building block for the synthesis of novel, targeted therapeutic agents, particularly in oncology and anti-inflammatory drug discovery pipelines. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing small-molecule drugs and kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Serves as a core scaffold in the design and production of potent and selective kinase inhibitors for targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in biochemical assays and high-throughput screening to study enzyme function and identify new drug targets.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to the specific needs of drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	(6-Fluoro-2-Methyl-4-Oxo-4H-Quinazolin-3-Yl)-Acetic Acid
CAS No.	1322605-08-2
Molecular Formula	C₁₁H₉FN₂O₃
Molecular Weight	236.20 g/mol
Synonyms	2-(6-Fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)acetic acid; 3-Carboxymethyl-6-fluoro-2-methyl-3,4-dihydroquinazolin-4-one; 6-Fluoro-2-methyl-4-oxo-3,4-dihydroquinazoline-3-acetic acid; (6-Fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)acetic acid; Quinazolin-3-yl-acetic acid derivative; FMQA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (6-Fluoro-2-Methyl-4-Oxo-4H-Quinazolin-3-Yl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.