Description

(5-tert-Butyl-1,2,4-Oxadiazol-3-Yl)Methanamine Hydrochloride is a high-purity, functionalized oxadiazole derivative supplied as a stable hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the unique 1,2,4-oxadiazole pharmacophore into novel active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its reactive amine group and the bioisosteric properties of the 1,2,4-oxadiazole ring.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new herbicides, fungicides, and insecticides.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in coordination chemistry and catalysis.
• Custom Synthesis and Contract Manufacturing: A starting material for the custom synthesis of complex, high-value specialty chemicals for clients.

Basic Information

Product Name	(5-tert-Butyl-1,2,4-Oxadiazol-3-Yl)Methanamine Hydrochloride
CAS No.	1315366-45-0
Molecular Formula	C7H14N3O·HCl
Molecular Weight	191.67 g/mol (Free base: 156.21 g/mol)
Synonyms	1-(5-tert-Butyl-1,2,4-oxadiazol-3-yl)methanamine hydrochloride; 3-(Aminomethyl)-5-tert-butyl-1,2,4-oxadiazole hydrochloride; (5-tert-Butyl-[1,2,4]oxadiazol-3-yl)-methylamine hydrochloride; 5-tert-Butyl-1,2,4-oxadiazole-3-methanamine HCl; 3-(Aminomethyl)-5-(1,1-dimethylethyl)-1,2,4-oxadiazole hydrochloride
EINECS	Contact for details

Quality Control

Our (5-tert-Butyl-1,2,4-Oxadiazol-3-Yl)Methanamine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.