Description

1,3-Cyclobutanediamine Dihydrochloride is a high-purity, crystalline organic salt derived from the rigid cyclobutane scaffold. This compound matters as a versatile and valuable chiral building block for the synthesis of complex pharmaceutical intermediates and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infectives.
• Ligand Synthesis: Used to prepare novel chiral ligands and catalysts for asymmetric synthesis, enhancing enantioselectivity in critical bond-forming reactions.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for developing specialty polymers with unique thermal and mechanical properties.
• Agrochemical Research: Employed in the design and synthesis of new herbicide and pesticide candidates, leveraging its constrained diamine structure.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Coordination Chemistry: Functions as a chelating agent for metal ions, useful in creating metal-organic frameworks (MOFs) or catalytic complexes.

Basic Information

Item	Details
Product Name	1,3-Cyclobutanediamine Dihydrochloride
CAS No.	1314772-13-8
Molecular Formula	C4H12Cl2N2
Molecular Weight	159.06 g/mol
Synonyms	1,3-Diaminocyclobutane Dihydrochloride; (1r,3r)-1,3-Cyclobutanediamine Dihydrochloride; (1s,3s)-1,3-Cyclobutanediamine Dihydrochloride; trans-1,3-Cyclobutanediamine Dihydrochloride; 1,3-CBDA-2HCl; Cyclobutane-1,3-diamine Dihydrochloride; 1,3-Cyclobutanediamine, Hydrochloride (1:2); 1,3-Cyclobutylenediamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,3-Cyclobutanediamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.