Description

6-Bromoquinoline-3-Carbonitrile is a high-purity, versatile brominated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the bromine and nitrile functional groups, which enable precise, site-specific coupling and functionalization reactions essential for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Catalyst & Ligand Development: Employed in the design and synthesis of novel nitrogen-containing ligands for transition metal catalysis.
• Chemical Research: A versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyano-group transformations in academic and industrial R&D.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and colorants.

Basic Information

Product Name	6-Bromoquinoline-3-Carbonitrile
CAS No.	1314687-82-5
Molecular Formula	C10H5BrN2
Molecular Weight	233.07 g/mol
Synonyms	3-Cyano-6-bromoquinoline; 6-Bromo-3-quinolinecarbonitrile; 6-Bromoquinoline-3-carbonitrile; Quinoline, 6-bromo-3-cyano-; 1314687-82-5; 6-Bromo-quinoline-3-carbonitrile; 6-Brom-3-chinolinecarbonitril (German); 6-Bromo-3-cyanoquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromoquinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.