Description

Spiro[2.5]Octane-5-Carboxylic Acid is a specialized spirocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique, rigid spirocyclic framework makes it a valuable precursor for constructing complex molecular architectures with defined three-dimensional geometry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand design, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral or constrained scaffold in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its spirocyclic structure can impart unique biological activity and stability.
• Ligand and Catalyst Synthesis: Acts as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of advanced polymers, liquid crystals, and other functional organic materials requiring rigid, three-dimensional components.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags to study biological systems and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	Spiro[2.5]Octane-5-Carboxylic Acid
CAS No.	1314390-66-3
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	Spiro[2.5]octane-5-carboxylic acid; 5-Carboxyspiro[2.5]octane; 1-Oxaspiro[2.5]octane-5-carboxylic acid (related bicyclic form); Spirocyclic C5-carboxylic acid; 5-Spiro[2.5]octanecarboxylic acid; Bicyclo[3.1.1]heptane-6-carboxylic acid, 2-oxa- (alternative systematic name); 1314390-66-3
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Octane-5-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.