Description

(S)-4-(Pyrrolidin-3-Yloxy)Pyridine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new bioactive molecules.
• Ligand and Probe Synthesis: Serves as a precursor for creating specialized chemical probes or ligands for biological target validation.
• Asymmetric Synthesis: Employed in catalytic or stoichiometric asymmetric reactions to introduce chirality into more complex molecular architectures.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	(S)-4-(Pyrrolidin-3-Yloxy)Pyridine Hydrochloride
CAS No.	1314355-43-5
Molecular Formula	C9H13ClN2O
Molecular Weight	200.67 g/mol
Synonyms	(S)-4-(3-Pyrrolidinyloxy)pyridine hydrochloride; (S)-4-(Pyrrolidin-3-yloxy)pyridine HCl; Pyridine, 4-[(3S)-3-pyrrolidinyloxy]-, hydrochloride; (S)-4-(3-Pyrrolidinoloxy)pyridine hydrochloride; (S)-4-(Pyrrolidin-3-oxy)pyridine hydrochloride; (S)-4-(Pyrrolidin-3-yloxy)pyridine monohydrochloride
EINECS	Contact for details

Quality Control

Our (S)-4-(Pyrrolidin-3-Yloxy)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.