Description

(R)-3-Boc-4-Benzyl-1,2,3-Oxathiazolidine 2,2-Dioxide CAS NO 1313705-91-7 is a high-purity chiral sulfamidate building block, primarily utilized as a key intermediate in asymmetric synthesis. Its value lies in enabling the stereoselective introduction of nitrogen functionalities, which is critical for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules requiring precise stereochemistry.

Application

• Chiral Auxiliary and Building Block: Serves as a versatile intermediate for the stereocontrolled synthesis of amines and amino alcohols.
• Pharmaceutical Intermediate: A key precursor in the development of novel APIs, especially for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides, fungicides, and insecticides.
• Asymmetric Catalysis Research: Employed in academic and industrial R&D for developing new catalytic methodologies and ligand systems.
• Peptidomimetics and PROTACs: Facilitates the construction of complex peptide-like molecules and proteolysis-targeting chimeras.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high enantiomeric purity.

Basic Information

Product Name	(R)-3-Boc-4-Benzyl-1,2,3-Oxathiazolidine 2,2-Dioxide
CAS No.	1313705-91-7
Molecular Formula	C₁₅H₂₁NO₅S
Molecular Weight	327.40 g/mol
Synonyms	(R)-3-(tert-Butoxycarbonyl)-4-benzyl-1,2,3-oxathiazolidine 2,2-dioxide; (R)-N-Boc-4-benzyl-1,2,3-oxathiazolidine 2,2-dioxide; (R)-3-Boc-4-benzyl-1,2,3-oxathiazolidine-2,2-dioxide; (R)-4-Benzyl-3-(tert-butoxycarbonyl)-1,2,3-oxathiazolidine 2,2-dioxide; (R)-tert-Butyl 4-benzyl-2,2-dioxo-1,2,3-oxathiazolidine-3-carboxylate; (R)-Boc-4-Bn-sultam; (R)-Boc-Benzyl-sultam; (R)-Boc-4-Benzylsultam
EINECS	Contact for details

Quality Control

Our (R)-3-Boc-4-Benzyl-1,2,3-Oxathiazolidine 2,2-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.