Description

6-Chloro-1,5-Naphthyridin-4-Ol is a high-purity, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. This naphthyridine derivative is valued for its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological or material properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, or photoactive materials in advanced material applications.
• Academic & Contract Research: Employed in university and CRO laboratories for method development, structure-activity relationship (SAR) studies, and novel synthetic route exploration.
• Chemical Library Synthesis: Used for the generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	6-Chloro-1,5-Naphthyridin-4-Ol
CAS No.	1312760-59-0
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	6-Chloro-1,5-naphthyridin-4-ol; 4-Hydroxy-6-chloro-1,5-naphthyridine; 6-Chloro-4-hydroxy-1,5-naphthyridine; 1,5-Naphthyridin-4-ol, 6-chloro-; 6-Chloro-1,5-naphthyridin-4(1H)-one (tautomer); 6-Chloro-4(1H)-oxo-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,5-Naphthyridin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.