Description

tert-Butyl6-Bromoquinolin-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for oncology and antiviral applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline scaffold into more complex molecular architectures.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial research for studying structure-activity relationships (SAR).
• Agrochemical Research: Potential intermediate in the development of new crop protection agents due to the bioactive quinoline structure.
• Material Science: Can be utilized in the synthesis of organic ligands for catalytic systems or functional materials.

Basic Information

Product Name	tert-Butyl6-Bromoquinolin-2-Ylcarbamate
CAS No.	1312611-18-9
Molecular Formula	C₁₄H₁₅BrN₂O₂
Molecular Weight	323.19 g/mol
Synonyms	6-Bromo-2-[(tert-butoxycarbonyl)amino]quinoline; 2-Quinolinecarboxamide, 6-bromo-N-(1,1-dimethylethoxy)-; tert-Butyl (6-bromoquinolin-2-yl)carbamate; 6-Bromo-N-Boc-quinolin-2-amine; Boc-6-Bromo-2-aminoquinoline; 1312611-18-9; (6-Bromoquinolin-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl6-Bromoquinolin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.