Description

(+)-Dichloro[(4R)-4-(I-Propyl)-2-{(R)-2-(Diphenylphosphino)Ferrocenyl}Oxazoline](Triphenylphosphine)Ruthenium(II) is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters for its exceptional enantioselectivity and catalytic efficiency in key synthetic transformations, enabling the production of high-value, optically pure intermediates. It is primarily needed by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries for advanced process development.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Critical for constructing stereogenic centers in active pharmaceutical ingredients (APIs), including chiral drugs for cardiovascular and central nervous system disorders.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the cost-effective and selective synthesis of complex chiral molecules for flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Employed to develop scalable, efficient, and sustainable manufacturing routes for chiral compounds.

Basic Information

Product Name	(+)-Dichloro[(4R)-4-(I-Propyl)-2-{(R)-2-(Diphenylphosphino)Ferrocenyl}Oxazoline](Triphenylphosphine)Ruthenium(II)
CAS No.	1312582-16-3
Molecular Formula	C46H43Cl2FeNOP2Ru
Molecular Weight	882.61 g/mol
Synonyms	(R)-[(S)-4-Isopropyl-2-(2-(diphenylphosphino)ferrocenyl)oxazoline](triphenylphosphine)ruthenium(II) dichloride; Ru-Phox Catalyst; Josiphos-type Ru Catalyst; Chiral Ruthenium Josiphos Complex; (R)-[(S)-4-iPr-2-(2-(PPh2)ferrocenyl)oxazoline](PPh3)RuCl2; Asymmetric Hydrogenation Catalyst Ru(S)-Josiphos; [RuCl2((R)-4-iPr-2-((S)-2-(diphenylphosphino)ferrocenyl)oxazoline)(PPh3)]
EINECS	Contact for details

Quality Control

Our (+)-Dichloro[(4R)-4-(I-Propyl)-2-{(R)-2-(Diphenylphosphino)Ferrocenyl}Oxazoline](Triphenylphosphine)Ruthenium(II) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for sensitive catalytic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light will degrade catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Solubility	Soluble in dichloromethane, toluene; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.