Description

4-Chloro-2-Iodo-1-Methyl-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex, functionalized molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated structure.
• Material Science Precursor: Serves as a specialized monomer or precursor for creating functional organic materials and ligands for catalysis.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for HTS: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Item	Details
Product Name	4-Chloro-2-Iodo-1-Methyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1312581-09-1
Molecular Formula	C8H6ClIN2
Molecular Weight	308.50 g/mol
Synonyms	4-Chloro-2-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridine; 1-Methyl-4-chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-2-iodo-1-methyl-7-azaindole; 7-Azaindole, 4-chloro-2-iodo-1-methyl-; Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-1-methyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodo-1-Methyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.