Description

(S)-1-(4-Bromo-2-Fluorophenyl)Ethanamine Hydrochloride CAS NO 1311254-85-9 is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. Its value lies in its role as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies. This compound is primarily needed by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drugs, especially in areas requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and the creation of enantiomerically pure drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced, targeted pesticides and herbicides.
• Ligand & Catalyst Development: Employed in the research and synthesis of chiral ligands for asymmetric catalysis.
• Chemical Biology Research: Utilized as a molecular probe or scaffold in studying biological pathways and protein interactions.
• Fine Chemical Manufacturing: A key raw material for producing specialized, high-value chemicals with specific stereochemistry.

Basic Information

Item	Detail
Product Name	(S)-1-(4-Bromo-2-Fluorophenyl)Ethanamine Hydrochloride
CAS No.	1311254-85-9
Molecular Formula	C8H10BrClFN
Molecular Weight	254.53 g/mol
Synonyms	(S)-1-(4-Bromo-2-fluorophenyl)ethan-1-amine hydrochloride; (S)-α-Methyl-4-bromo-2-fluorobenzylamine hydrochloride; (S)-1-(4-Bromo-2-fluorophenyl)ethylamine HCl; (S)-4'-Bromo-2'-fluoro-α-methylbenzylamine hydrochloride; (S)-1-Aminoethyl-4-bromo-2-fluorobenzene hydrochloride; (S)-1-(4-Bromo-2-fluorophenyl)ethanamine HCl salt
EINECS	Contact for details

Quality Control

Our (S)-1-(4-Bromo-2-Fluorophenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.