Description

9-Hydroxy-5-Methyl-6.7-Diaza-Spiro[3.5]Non-5-En-8-One is a high-value, structurally complex spirocyclic compound featuring a fused diaza ring system. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry, enabling the development of novel bioactive molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its three-dimensional, spirocyclic architecture.
• Agrochemical Research: Serves as a precursor for developing new crop protection agents with potential herbicidal or insecticidal activity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for fundamental organic synthesis and methodology development.
• Fine Chemical Production: Acts as a starting material for the manufacture of other complex, high-value specialty chemicals.

Basic Information

Product Name	9-Hydroxy-5-Methyl-6.7-Diaza-Spiro[3.5]Non-5-En-8-One
CAS No.	1311254-49-5
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	5-Methyl-6,7-diaza-spiro[3.5]non-5-ene-8,9-dione, 9-Hydroxy derivative; 9-Hydroxy-5-methyl-6,7-diazaspiro[3.5]non-5-en-8-one; 5-Methyl-9-hydroxy-6,7-diazaspiro[3.5]non-5-en-8-one; Spiro[3.5]nonane-8,9-dione, 5-methyl-6,7-diaza-, 9-ol; 1311254-49-5; 9-Hydroxy-5-methyl-6,7-diaza-spiro[3.5]non-5-en-8-one
EINECS	Contact for details

Quality Control

Our 9-Hydroxy-5-Methyl-6.7-Diaza-Spiro[3.5]Non-5-En-8-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades (from research grade to GMP standard) to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage of bulk quantities.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.