Description

(S)-(4-Chlorophenyl)(Cyclopropyl)Methanamine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in modern pharmaceutical synthesis. Its value lies in providing a defined stereocenter essential for creating enantiomerically pure active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the construction of complex molecules for potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric reactions to introduce chirality into target molecules.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Acts as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(S)-(4-Chlorophenyl)(Cyclopropyl)Methanamine Hydrochloride
CAS No.	1310923-26-2
Molecular Formula	C10H13ClN • HCl
Molecular Weight	218.13 g/mol (free base: 181.67 g/mol)
Synonyms	(S)-1-(4-Chlorophenyl)-1-cyclopropylmethanamine hydrochloride; (S)-α-(4-Chlorophenyl)-cyclopropanemethylamine hydrochloride; (S)-CPMA HCl; (1S)-1-(4-Chlorophenyl)-1-cyclopropylmethanamine hydrochloride; (S)-1-Cyclopropyl-1-(4-chlorophenyl)methanamine hydrochloride; (S)-4-Chlorophenyl(cyclopropyl)methanamine hydrochloride; (S)-Amino(4-chlorophenyl)(cyclopropyl)methane hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(4-Chlorophenyl)(Cyclopropyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.