Description

(R)-1-(2,6-Difluorophenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of enantiomerically pure drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, especially for neurological and psychiatric applications.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions.
• Agrochemical Research: Serves as a building block for developing new enantiopure pesticides and herbicides.
• Ligand Synthesis: Precursor for chiral ligands used in catalysis, such as for asymmetric hydrogenation.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in regulatory submissions.
• Peptidomimetics: Incorporated into the design of novel peptide-like molecules for drug discovery.

Basic Information

Product Name	(R)-1-(2,6-Difluorophenyl)Ethanamine Hydrochloride
CAS No.	1309598-72-8
Molecular Formula	C8H10ClF2N
Molecular Weight	193.62 g/mol
Synonyms	(R)-1-(2,6-Difluorophenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-2,6-difluorobenzylamine hydrochloride; (R)-2,6-Difluoro-α-methylbenzylamine hydrochloride; (R)-1-(2,6-Difluorophenyl)ethylamine hydrochloride; (R)-1-Aminoethyl-2,6-difluorobenzene hydrochloride; (R)-1-(2,6-Difluorophenyl)ethanamine HCl; (R)-2,6-DFBA HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(2,6-Difluorophenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.