Description

2-Chloro-N-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]acetamide is a specialized pyridine-based acetamide derivative that serves as a critical synthetic intermediate in advanced chemical manufacturing. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic disorders.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethylpyridine moiety for enhanced bioactivity and environmental stability.
• Chemical Synthesis Reagent: Serves as a versatile electrophile or amide coupling partner in complex organic synthesis for academic and industrial research.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Chloro-N-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]acetamide
CAS No.	1308649-80-0
Molecular Formula	C9H8ClF3N2O
Molecular Weight	252.62 g/mol
Synonyms	2-Chloro-N-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)acetamide; 2-Chloroacetamide, N-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-; 3-Acetamido-2-methyl-6-trifluoromethylpyridine, 2-chloro derivative; 2-Chloro-N-(2-methyl-6-(trifluoromethyl)-3-pyridinyl)acetamide; Acetamide, 2-chloro-N-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.