Description

tert-Butyl 1-Methyl-1,4,9-Triazaspiro[5.5]Undecane-9-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic triaza scaffold. This compound is critical for medicinal chemistry research and development, serving as a sophisticated building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers focused on developing therapeutics in areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Incorporated into the final molecular structure of potential new chemical entities (NCEs), particularly those targeting neurological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological mechanisms and target validation.

Basic Information

Product Name	tert-Butyl 1-Methyl-1,4,9-Triazaspiro[5.5]Undecane-9-Carboxylate
CAS No.	1308384-37-3
Molecular Formula	C14H27N3O2
Molecular Weight	269.39 g/mol
Synonyms	1,4,9-Triazaspiro[5.5]undecane-9-carboxylic acid, 1-methyl-, 1,1-dimethylethyl ester; tert-Butyl 1-methyl-1,4,9-triazaspiro[5.5]undecane-9-carboxylate; 1-Methyl-1,4,9-triazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester; 9-Boc-1-methyl-1,4,9-triazaspiro[5.5]undecane; 1-Methyl-9-Boc-1,4,9-triazaspiro[5.5]undecane; Spirocyclic triaza building block
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 1-Methyl-1,4,9-Triazaspiro[5.5]Undecane-9-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.