Description

JWH-018 5-Hydroxyindole Metabolite is a key analytical reference standard, specifically the 5-hydroxylated metabolite of the synthetic cannabinoid JWH-018. This compound is of critical importance for forensic, clinical, and research laboratories requiring precise analytical standards for metabolite identification and quantification. It is primarily needed by analytical chemists and toxicologists in forensic science, clinical toxicology, and pharmaceutical research for method development and validation in drug testing protocols.

Application

• Forensic Toxicology Reference Standard: Used as a certified reference material (CRM) for the identification and confirmation of JWH-018 metabolite presence in biological samples (e.g., urine, blood, serum).
• Clinical Research & Method Development: Essential for developing and validating sensitive analytical methods, such as LC-MS/MS or GC-MS, for detecting synthetic cannabinoid use in clinical and workplace testing.
• Pharmaceutical Impurity Profiling: Serves as a characterized impurity or metabolite standard in pharmaceutical research related to cannabinoid receptor studies.
• Quality Control & Assurance: Employed by manufacturers of diagnostic kits and testing laboratories to ensure the accuracy and reliability of their synthetic cannabinoid assay panels.
• Academic & Governmental Research: Utilized in studies investigating the metabolism, pharmacokinetics, and long-term effects of synthetic cannabinoids on human health.

Basic Information

Product Name	JWH-018 5-Hydroxyindole Metabolite
CAS No.	1307803-43-5
Molecular Formula	C24H23NO2
Molecular Weight	357.45 g/mol
Synonyms	(1-Pentyl-1H-indol-3-yl)(1-hydroxynaphthalen-2-yl)methanone; 5-Hydroxy JWH-018; JWH-018 N-(5-hydroxypentyl) metabolite; JWH-018 5-OH Indole; 2-[(1-Pentyl-1H-indol-3-yl)carbonyl]-1-naphthalenol; N-(5-Hydroxypentyl)-JWH-018 metabolite
EINECS	Contact for details

Quality Control

Our reference standards are produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided, listing batch-specific data for purity, impurities, and analytical methods. We ensure traceability and compliance with relevant guidelines for forensic and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storage at -20°C is recommended. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.