Description

Spiro[Piperidine-4,7'-[7H]Thieno[2,3-C]Pyran], 2'-Chloro-4',5'-Dihydro- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1307381-31-2. This compound is valued for its complex spirocyclic and heterocyclic architecture, which serves as a critical building block in modern medicinal chemistry. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

This specialized intermediate is designed for high-value synthetic applications, particularly in drug discovery and development.

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential therapeutic agents, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and reaction methodologies.
• Library Synthesis: Employed in the construction of diverse compound libraries for high-throughput screening against biological targets.

Basic Information

Item	Details
Product Name	Spiro[Piperidine-4,7'-[7H]Thieno[2,3-C]Pyran], 2'-Chloro-4',5'-Dihydro-
CAS No.	1307381-31-2
Molecular Formula	C12H14ClNOS
Molecular Weight	255.76 g/mol
Synonyms	2'-Chloro-4',5'-dihydrospiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran]; 2'-Chloro-4',5'-dihydro-7'H-spiro[piperidine-4,7'-thieno[2,3-c]pyran]; Spiro[piperidine-4,7'-thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro-; 1307381-31-2; 2-Chloro-4,5-dihydro-7H-spiro[thieno[2,3-c]pyran-7,4'-piperidine]; 2'-Chloro-4',5'-dihydrospiro[1-azabicyclo[3.3.1]nonane-9,7'-[7H]thieno[2,3-c]pyran] (related structure)
EINECS	Contact for details

Quality Control

Our Spiro[Piperidine-4,7'-[7H]Thieno[2,3-C]Pyran], 2'-Chloro-4',5'-Dihydro- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for your grade.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.