Description

(R)-4-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is a high-purity chiral amine building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of enantiomerically pure therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, especially in neuroscience.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	(R)-4-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	1307231-02-2
Molecular Formula	C9H11BrClN
Molecular Weight	248.55 g/mol
Synonyms	(1R)-4-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride; (R)-4-Bromoindan-1-amine hydrochloride; (R)-1-Amino-4-bromoindane hydrochloride; 4-Bromo-(1R)-indan-1-amine hydrochloride; (R)-4-Bromo-1-indanamine hydrochloride; (1R)-4-Bromo-2,3-dihydro-1H-inden-1-amine HCl; 1307231-02-2; 4-Bromo-(R)-1-aminoindane hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-4-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.