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4-Chloro-5-Fluoro-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine CAS NO 1305324-87-1


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CAS No.:1305324-87-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloro-5-Fluoro-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-halogenated pyrrolopyridine derivative that serves as a critical building block in modern synthetic chemistry. Its complex heterocyclic structure, featuring chlorine, fluorine, and iodine substituents, makes it an indispensable intermediate for constructing sophisticated molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other biologically active heterocycles.
  • Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides due to its halogen-rich scaffold.
  • Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
  • Chemical Synthesis: Enables complex cross-coupling reactions (e.g., Suzuki, Sonogashira) and functional group transformations in medicinal and process chemistry.
  • Academic & Contract Research: Utilized in universities and CROs for methodological development and exploring new chemical spaces.

Basic Information

Product Name 4-Chloro-5-Fluoro-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No. 1305324-87-1
Molecular Formula C13H7ClFINO2S
Molecular Weight 447.62 g/mol
Synonyms 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-3-iodo-1-(phenylsulfonyl)-; 4-Chloro-5-fluoro-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-4-chloro-5-fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-fluoro-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; CAS 1305324-87-1
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Quality Control

Our production of 4-Chloro-5-Fluoro-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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