Description

Glcnac Beta(1-3)[Glcnac Beta(1-6)]Galnac-α-Thr is a complex, synthetic oligosaccharide derivative, specifically a glycosylated threonine building block. This compound is of significant value in glycobiology research and bioconjugate chemistry for the study and synthesis of O-linked glycoproteins. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who are developing novel glycotherapeutics, vaccines, or advanced analytical standards.

Application

• Glycobiology Research: A critical tool for studying enzyme kinetics, substrate specificity, and inhibition of glycosyltransferases involved in O-glycan biosynthesis.
• Bioconjugate Synthesis: Serves as a key intermediate or building block for the chemical or enzymatic synthesis of complex, defined O-linked glycopeptides and glycoproteins.
• Pharmaceutical Development: Used in the research and development of glycoprotein-based therapeutics, including monoclonal antibodies, hormones, and enzyme replacement therapies.
• Diagnostic Reagent Production: Employed in the manufacture of high-purity standards and reagents for diagnostic assays targeting specific glycan biomarkers.
• Enzyme Substrate/Inhibitor: Acts as a specific substrate for glycosidases or glycosyltransferases, or as a starting point for designing potent enzyme inhibitors.
• Academic Research: Fundamental research into cell signaling, protein folding, stability, and immune recognition mediated by O-glycosylation.

Basic Information

Product Name	Glcnac Beta(1-3)[Glcnac Beta(1-6)]Galnac-α-Thr
CAS No.	1304646-03-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl-(1→3)-[2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→6)]-2-acetamido-2-deoxy-α-D-galactopyranosyl)-L-threonine; (GlcNAcβ1-3[GlcNAcβ1-6]GalNAcα1-O)-Thr; Glycosylated Threonine Derivative; Core 2 O-Glycan Trisaccharide-Thr; Synthetic O-Glycan Building Block
EINECS	Contact for details

Quality Control

Every batch of Glcnac Beta(1-3)[Glcnac Beta(1-6)]Galnac-α-Thr is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a desiccated environment to prevent moisture absorption and degradation. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.