Description

4-Azaspiro[2,5]Octane Hcl is a high-purity, nitrogen-containing spirocyclic building block essential for modern organic synthesis. This compound matters as a versatile scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and infectious diseases.
• Medicinal Chemistry Scaffold: Used as a privileged spirocyclic structure to explore new chemical space and improve the pharmacokinetic properties of lead compounds.
• Agrochemical Research: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal activity.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Employed in the creation of novel chiral ligands for asymmetric synthesis and transition metal catalysis.
• Advanced Material Precursor: A potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	4-Azaspiro[2,5]Octane Hcl
CAS No.	1301739-56-9
Molecular Formula	C7H14ClN
Molecular Weight	147.65 g/mol
Synonyms	4-Azaspiro[2.5]octane hydrochloride; 1-Azaspiro[2.5]octane hydrochloride; 4-Azaspiro[2,5]octane, hydrochloride; 4-Aza-spiro[2.5]octane HCl; Spiro[cyclopropane-1,2'-piperidine] hydrochloride; 1'-Azaspiro[cyclopropane-1,2'-piperidine] hydrochloride; 4-Azaspiro[2.5]octane HCl salt
EINECS	Contact for details

Quality Control

Our 4-Azaspiro[2,5]Octane Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.