Description

(1R,2R)-1,2-Diamino-1,2-Dimesitylethane Dihydrochloride is a high-purity, chiral diamine derivative used as a sophisticated ligand and building block in advanced chemical synthesis. Its value lies in providing a rigid, sterically hindered framework that is critical for inducing high enantioselectivity in catalytic reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel catalysts, chiral auxiliaries, and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand for transition metal catalysts in enantioselective hydrogenation, C-C bond formation, and other key transformations.
• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex, chiral drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organocatalyst Synthesis: Used to construct chiral organocatalysts for green chemistry applications that do not require metal centers.
• Material Science Research: Employed in the development of chiral metal-organic frameworks (MOFs) and polymers with specific optical or separation properties.
• Analytical Chiral Stationary Phases: Can be immobilized on silica to create high-performance liquid chromatography (HPLC) columns for enantiomer separation.

Basic Information

Product Name	(1R,2R)-1,2-Diamino-1,2-Dimesitylethane Dihydrochloride
CAS No.	1301706-47-7
Molecular Formula	C₂₂H₃₂Cl₂N₂
Molecular Weight	395.41 g/mol
Synonyms	(1R,2R)-1,2-Bis(2,4,6-trimethylphenyl)ethane-1,2-diamine dihydrochloride; (R,R)-1,2-Diamino-1,2-dimesitylethane Dihydrochloride; (R,R)-DADME Dihydrochloride; (1R,2R)-DADME·2HCl; (R,R)-1,2-Dimesitylethylenediamine Dihydrochloride; (1R,2R)-1,2-Bis(mesityl)ethylenediamine Dihydrochloride; Chiral Dimesitylethylenediamine Salt
EINECS	Contact for details

Quality Control

Every batch of (1R,2R)-1,2-Diamino-1,2-Dimesitylethane Dihydrochloride is produced and tested under strict quality management systems to ensure consistent high purity and chiral integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing chiral purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.