Description

4-(4-Chloro-6-Methoxy-3-Nitroquinolin-7-Yl)-3,5-Dimethylisoxazole is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block in synthesizing targeted small molecule drugs. It is primarily needed by R&D laboratories, contract research organizations (CROs), and active pharmaceutical ingredient (API) manufacturers working in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel quinoline-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of potential drug molecules.
• Oncology Drug Development: Employed as a building block for creating targeted kinase inhibitors and other anti-cancer agents.
• Contract Synthesis: Supplied to CROs and CDMOs for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and bioactivity.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	4-(4-Chloro-6-Methoxy-3-Nitroquinolin-7-Yl)-3,5-Dimethylisoxazole
CAS No.	1300031-65-5
Molecular Formula	C₁₅H₁₂ClN₃O₄
Molecular Weight	333.73 g/mol
Synonyms	4-(4-Chloro-6-methoxy-3-nitroquinolin-7-yl)-3,5-dimethylisoxazole; 7-(3,5-Dimethylisoxazol-4-yl)-4-chloro-6-methoxy-3-nitroquinoline; 4-Chloro-6-methoxy-7-(3,5-dimethyl-4-isoxazolyl)-3-nitroquinoline; 1300031-65-5; 4-(4-Chloro-6-methoxy-3-nitro-7-quinolinyl)-3,5-dimethylisoxazole
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-6-Methoxy-3-Nitroquinolin-7-Yl)-3,5-Dimethylisoxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.