Description

6-Iodo-5-Methoxypyridin-3-Ol is a versatile and high-value iodinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated methoxypyridine structure makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is particularly valuable for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated heterocyclic core.
• Ligand Synthesis: Acts as a starting material for creating sophisticated ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as OLEDs and semiconductors, due to its electron-rich pyridine system.
• Cross-Coupling Reactions: The iodine atom provides an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes.

Basic Information

Product Name	6-Iodo-5-Methoxypyridin-3-Ol
CAS No.	1299607-66-1
Molecular Formula	C6H6INO2
Molecular Weight	250.02 g/mol
Synonyms	5-Methoxy-6-iodopyridin-3-ol; 3-Hydroxy-5-methoxy-6-iodopyridine; 6-Iodo-5-methoxy-3-pyridinol; 5-Methoxy-6-iodo-3-hydroxypyridine; 3-Pyridinol, 6-iodo-5-methoxy-; 6-Iodo-5-methoxypyridin-3-ol; 1299607-66-1
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-5-Methoxypyridin-3-Ol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.